Postoperative day (POD)1, POD2, postoperative week (POW)1, and postoperative month (POM)1. Furthermore, if a significant difference was identified, one-way factorial ANOVA and the Tukey-Kramer test were used to pinpoint which factors were significantly different. Statistical analysis was performed using statistical software programmed by Hisae Yanai (Statcal-3; OMS Publication, Saitama, Japan) along with Excel software (Microsoft, Redmond, WA). Values of p less than 0.05 were considered statistically significant.Results The indications for surgery are shown in Table 1 and mean values for each factor are summarized in Table 2. Mean axial length was 24.7 mm (range, Rupintrivir 22.62?2.64 mm) in Group A, 25.2 mm (range, 22.05?2.45 mm) in Group B, and 23.9 mm (range, 22.05?6.92 mm) in Group C. On the other hand, mean surgical time was 78.4 min (range, 44?24 min) in Group A, 70.9 min (range, 32?05 min) in Group B, and 36.2 min (range, 26?3 min) in Group C. No significant differences were seen among groups in age (p = 0.74; one-way factorial ANOVA) or axial length (p = 0.56; one-way factorial ANOVA), but surgical time differed significantly between Group C and the otherTable 1 Indications for surgeryPVR Group A SO injection/self-sealing Group B SO injection/suture placement Group C SO removal/self-sealing 6 7 5 PDR 4 2groups (p < 0.05; Tukey-Kramer test). Mean duration of SO tamponade was 3.2 ?1.4 months in Group C. No sclerotomies in Group A or C required suture placement. Postoperative PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/25676869 SO leakage to the subconjunctival space was not encountered in Group A. In cases of combined surgery (phacoemulsification and vitrectomy), intra- or postoperative complications of anterior segment such as hyphema or papillary block due to fibrinous iritis were not occurred. Postoperative IOPs in each period are summarized in Table 3, and a column graph for all cases at POD1 are provided in Fig. 1, with no cases showing postoperative hypotony (defined as IOP <5 mmHg). In comparisons of IOP using repeated-measures ANOVA, no significant differences were identified between Groups A and B for either variation between subgroups (p = 0.80) or variation within subgroups (p = 0.72), while a significant difference was noted between Groups A and C for variation between subgroups (p < 0.05), but not for variation within subgroups (p = 0.24). Additional statistical examination PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/26398108 using one-way factorial ANOVA and the Tukey-Kramer test for the significant difference (variation between subgroups between Groups A and C) proved that significant differences in IOP within the same postoperative period (p < 0.05) had existed at POD1 and POD2, although not at POW1 or POM1.Additional file 1 (age, surgical time, axial length,and postoperative IOP in each case) is available.Discussion Severe sclerotomy leakage was not considered to be present postoperatively in this study, because no cases showed postoperative hypotony, and the sclerotomies in Groups A and C had achieved self-sealing with only restoration of the valve architecture because of the minimal vitreous incarceration due to thorough vitrectomy. However, Kapran et al. [15] reported a decrease in IOP caused by subclinical amounts of leakage in cases of self-sealing sclerotomies at 2 h postoperatively, although no significant difference was found between pre- and postoperative IOP on and after day 1. Hypotony on the day of surgery causes ciliochoroidal detachment [16], and once ciliochoroidal detachment has developed, several weeks is usuall.
